%A Clark, Neil R.
%A Ma'ayan, Avi
%T Introduction to Statistical Methods for Analyzing Large Data Sets: Gene-Set Enrichment Analysis
%0 Journal Article
%D 2011
%J Sci. Signal.
%R 10.1126/scisignal.2001966
%P tr4-
%V 4
%N 190
%U http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/190/tr4
%8 September 13, 2011
%X This Teaching Resource provides lecture notes, slides, and a problem set for a series of lectures introducing the mathematical concepts behind gene-set enrichment analysis (GSEA) and were part of a course entitled "Systems Biology: Biomedical Modeling." GSEA is a statistical functional enrichment analysis commonly applied to identify enrichment of biological functional categories in sets of ranked differentially expressed genes from genome-wide mRNA expression data sets.