| Investigator | Area of expertise | Affiliation |
| Ravi lyengar, PhD | Biochemistry and molecular biology of cell signaling systems, drug action, and modeling | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Upinder S. Bhalla, PhD | Computational biology, neuroscience computer sciences | Department of Neurobiology, National Centre for Biological Sciences, India |
| Guillermo Cecchi, PhD | Network sciences, parallel computing | IBM T.J. Watson Research Center |
| Stephen C. Cowin, PhD | Biomedical engineering; models of complex biological systems | Department of Mechanical Engineering, City College of New York, CUNY |
| Lakshmi A Devi, PhD | Pharmacology and biochemistry and molecular biology of drug addiction, neural functions | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Emilia Entcheva, PhD | Biomedical engineering, cardiac tissue function | Department of Biomedical Engineering, Stony Brook University, SUNY |
| Fernand Hayot, PhD | Applied mathematics, stochastic modeling | Department of Neurology, Mount Sinai School of Medicine |
| Samuel Isaacson, PhD | Applied mathematics, complex biological systems 3D modeling | Department of Mathematics, Boston University |
| Ehud Kaplan, PhD | Systems neurosciences, neural networks, electrophysiology/modeling | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Terry A. Krulwich, PhD | Biochemistry, pharmacology, bacterial energetic systems, bacteria-human interaction, interdisciplinary education | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Avi Ma'ayan, PhD | Bioinformatics, graph theory, software engineering, parallel computing (MPI) | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| David M. McQueen, PhD | Computer science, large-scale computation | Department of Mathematics, Courant Institute of Mathematical Sciences NYU |
| Susana R. Neves PhD | Cell signaling, cell imaging | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Charles S. Peskin, PhD | Applied mathematics, complex biological systems, modeling | Department of Mathematics, Courant Institute of Mathematical Sciences NYU |
| Suzanne Scarlata, PhD | Cell signaling, biophysics, live cell imaging | Department of Physiology and Biophysics, Stony Brook University, SUNY |
| Stuart C. Sealfon, MD | Neuronal signaling, drug receptor functions, multivariable experimentation | Department of Neurology, Mount Sinai School of Medicine |
| Lawrence Sirovich, PhD | Applied mathematics, mathematical models of biological systems | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Gillian M. Small, PhD | Cell Biology | City College of New York, CUNY |
| Eric A. Sobie, PhD | Biomedical engineering, computation cardiac function | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Gustavo A. Stolovitzky, PhD | Functional genomics, analyses of large datasets, network sciences and computing | IBM T.J. Watson Research Center |
| Chris Wiggins, PhD | Machine Learning, Statistical Inference, Information Theory for Biological networks | Department of Applied Physics and Applied Mathematics, Columbia University |